With critical limb ischemia (CLI) being a multi-factorial disease. it is becoming evident that gene therapy with a multiple bio-functional growth factor could achieve better therapeutic outcomes. Cytochrome P450 epoxygenase-2J2 (CYP2J2) and its catalytic products epoxyeicosatrienoic acids (EETs) exhibit pleiotropic biological activities. including pro-angiogenic. https://www.roneverhart.com/2003-2005-HONDA-ACCORD-2-4L-4-Cylinder-Engine-Upper-Intake-Manifold-OEM/