Solid tumors are characterized by a plethora of epigenetic changes. In particular. patterns methylation of cytosines at the 5-position (5mC) in the context of CpGs are frequently altered in tumors. Recent evidence suggests that 5mC can get converted to 5-hydroxylmethylcytosine (5hmC) in an enzymatic process involving ten eleven translocation (TET) protein family members. https://foldlyers.shop/product-category/rocker-switches/
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