The protein kinase Mec1 (ATR ortholog) and its partner Ddc2 (ATRIP ortholog) play a key role in DNA damage checkpoint responses in budding yeast. Previous studies have established the model in which Ddc1. a subunit of the checkpoint clamp. and Dpb11. https://www.roneverhart.com/Propper-Synergy-Wildland-Shirt/