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Antagonism of PP2A is an independent and conserved function of HIV-1 Vif and causes cell cycle arrest

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The seminal description of the cellular restriction factor APOBEC3G and its antagonism by HIV-1 Vif has underpinned two decades of research on the host-virus interaction. We recently reported that HIV-1 Vif is also able to degrade the PPP2R5 family of regulatory subunits of key cellular phosphatase PP2A (PPP2R5A-E; Greenwood et al. 2016; Naamati et al. https://www.tukangkacafilm.com/product-category/quickstrikes/
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